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Hypofibrinolysis in type 2 diabetes and its clinical implications: From mechanisms to pharmacological modulation

In the study, participants with a responsive genetic score had an 82% increase in the likelihood of acheiving weight loss with a GLP-1 medication.[ref] Another study showed that GLP1 receptor variants are associated with greater weight loss on GLP-1 RA drugs.[ref] Common genetic variants in the GLP1R (GLP-1 receptor) gene impact weight and type 2 diabetes risk

The practical implication: refrigerate, use within the labeled shelf life, and avoid exposing the vial to repeated temperature fluctuation