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This in turn has led to diabetes GLP-1 medications being prescribed off-label to promote weight loss in obese and overweight patients

Moreover, while DL-fed mice did show a trend towards cognitive improvements, it was clearly not as beneficial as CR

The medication is initiated at a lower dose and gradually titrated upward to minimize gastrointestinal side effects and optimize therapeutic response

"The only way to potentially avoid the weight rebound is to taper the GLP-1 slowly, while continuing other rigorous behavioral programs and lifestyle interventions, including diet and exercise," says Dr