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Unlike many weight loss compounds that work through appetite suppression or metabolic stimulation, AOD-9604 directly targets fat tissue at the receptor level, making it one of the most precise fat reduction tools available in peptide therapy

its overexpression significantly reduces GPX4 protein levels, exacerbating lipid peroxidation and ferroptosis, and targeted inhibition of METTL3 can affect the m6A modification level of GPX4, ultimately affecting cellular sensitivity to ferroptosis (Meng et al., 2024)

therefore, injecting an HA-based filler or biostimulators might cause excessive volumization

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