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Madsen MSA, Holm JB, Pallej A et al (2019) Metabolic and gut microbiome changes following GLP-1 or dual GLP-1/GLP-2 receptor agonist treatment in diet-induced obese mice

The evidence strongly supports implementing early response checkpoints at 4 weeks and prompt medication intervention for non-responders, challenging the traditional approach of prolonged behavioral therapy before pharmacological support

Important safety considerations include contraindications in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, caution in those with a history of pancreatitis, increased risk of gallbladder disease, potential for acute kidney injury with dehydration, and possible worsening of diabetic retinopathy with rapid glycemic improvement

Chia seeds pack omega-3 fatty acids, fiber, and protein into tiny packages