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Phase III trials were carried out as part of the SURPASS programme to investigate its therapeutic effectiveness (glycaemic control and body weight reduction) and safety/tolerability for the treatment of patients with type 2 diabetes [90, 91]

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A 2014 paper in the International Journal of Colorectal Disease reported a Phase 2 randomized controlled trial of ipamorelin for the management of postoperative ileus in bowel-resection patients, providing one of the few human-clinical-trial datasets for this class of molecule (PMID 25331030)