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To integrate possible mechanistic events, a unified proposal for the role of cuproptosis in Wilson disease is suggested: (1) Published data support that copper ions induce oxidative stress by generating ROS, including hydroxyl radicals and H 2 O 2 , via the Haber-Weiss and Fenton reactions [21,27,45-49,59,77,90-92]

However, if you have a B-12 deficiency, correcting low folate levels may simply mask the deficiency and fail to fix the underlying problem

10.1136/archdischild-2023-326049 17 DagherM.CahillC