viatris semaglutide AD/PD 2026: Novo Nordisk's fails to demonstrate any benefit for early Alzheimer's including heart disease Semaglutide — Weight Loss |

Tirzepatide tends to be the better fit when: the goal is more significant weight loss (15 percent or more of body weight), the patient has type 2 diabetes with A1C above target on prior therapies, prior single-pathway GLP-1 use produced limited results, or the patient tolerated GLP-1s reasonably well and wants a stronger next step

Certain parts of the body, such as the armpits and bikini area, may have darker hair that will respond well to treatment

Before the electrodes were surgically implanted, the doctors put her on tirzepatide, and she stayed on it afterward

1,2 Both drugs decreased HbA1c, reduced body weight, and provided cardiovascular benefits in pivotal Phase III trials