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Several methods for selecting control patients have been suggested, such as cardinality matching of individuals 15 based on propensity scoring 16 , which has become the preferred method for adjusting group differences and reducing confounding

250-252 In addition, assisted reproductive technique-conceived babies have been found to be more likely to experience perinatal problems (eg, low birth weight and preterm birth) compared with those conceived naturally, and some evidence suggests they may be at higher risk of cardiovascular problems later in life

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