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SdaA was reported to be the gene encoding either the structural gene of L-SD that catalyzes the deamination of serine to pyruvate or a positive activator of transcription [31]

The intestine, therefore, plays a central role in maintaining and regulating normal vitamin B 6 homeostasis

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The GPX family member glutathione peroxidase 4 (GPX4), the only isoenzyme that can reduce phospholipid hydroperoxide 6 , was considered one of the most important antioxidant enzymes in mammals 7