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Patient safety issues in the GLP-1 space this week On August 1st, a Reddit user was seeking advice and shared images of the recent shipment of tirzepatide that had changed color: International News Health Canada warning about unlicensed peptides and medicine counterfeiters busted in India and Uzbekistan

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A common pattern is this: softer carbs work better early, while denser, higher-fiber options are easier later in the day or once side effects ease

Glucose control The SURPASS studies enrolled populations that were similar in terms of baseline HbA1c levels, which ranged from 7.9 to 8.5% [2, 3, 59,60,61] and found a statistically significant reduction in HbA1c already at the 5 mg dose, demonstrating a greater efficacy of tirzepatide compared to placebo or active comparator [2, 3, 59,60,61]