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There is a body of evidence indicating that a lack of RIPK3 and MLKL expression can reduce kidney damage due to IRI, and the necroinflammation driven by RIPK3/MLKL-dependent necroptosis may lead to the progression of IRI to CKD [29]

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The following Table 1 compiles representative examples of such medicinal plants traditionally employed by local communities and indigenous tribes for GI issues such as ulcers, diarrhea, dyspepsia, constipation, gastritis, and colic, offering a practical overview of their cross-cultural relevance and therapeutic diversity

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