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In terms of GLP-1 receptor agonists (plus the mixed agonist-GIP modulator single case study), this similarly showed reduction in postprandial glucose peak and more appropriate insulin peak and timing after induction the intervention which subsequently responded to improved symptoms (total 7 patients) [29, 30]

Abstract Current pharmacological treatments for bipolar disorder are inadequate and based on serendipitously discovered drugs often with limited efficacy, burdensome side-effects, and unclear mechanisms of action

To address this, we developed a chimeric GLP-1A that targets transporter-mediated endocytosis to enhance cellular permeability to GLP-1A by utilizing the transporters available in the intestine, particularly the apical sodium-dependent bile acid transporter (ASBT)