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You want to pinch an area of fat, ensure the needle is inserted all the way, and keep the needle injected for a few seconds before pulling it out, so all the medication has been absorbed properly

There are no human clinical trials on ipamorelins ability to increase growth hormone (1)

As to the pain "going in" it may be that the needle caught a nerve or vein plus the fact that you were probably a little tense and nervous

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