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According to HealthCentral, many peptides lack solid human evidence and standardized dosing
Controlled trials of the protocol are not yet available
The product information available through the EMA states that the visceral abnormalities and major skeletal malformations seen after maternal exposure to semaglutide are probably due to embryotoxicity caused by a GLP-1 receptor-mediated impairment of the nutrient supply across the rat yolk sac, which has unclear translational significance for humans due to a difference in yolk sac anatomy
It is used in skincare because it tends to be more formulation friendly than pure vitamin C (ascorbic acid)
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