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What the Data Shows The Phase 2 trial of retatrutide, published in the New England Journal of Medicine in 2023, enrolled 338 adults with obesity or overweight with a weight-related condition (5)

Infections : Chronic infections deplete glutathione reserves as the body uses it to combat pathogens

Weight loss following dietary interventions and bariatric surgery is associated with changes to the circulating proteome, including proteins related to inflammatory and metabolic pathways 9,10