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As previously reported, AKT1 plays a key role in several cellular processes, including the regulation of mitochondrial dynamics by influencing the expression of proteins related to mitochondrial fusion and fission (Xie et al., 2022)

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Retinoids, peels, lasers, radiofrequency, ultrasound tightening, fillers, biostimulators, platelet-rich plasma or surgery may all have a role in selected patients