Age: With aging, muscle mass declines naturally (sarcopenia), tendons and ligaments shorten, and nerve function can decrease, all of which can predispose to more frequent leg cramps
Like other GLP-1 medications, Tirzepatide helps with weight loss by making you less hungry and making you feel full more easily
This novel treatment, nearing Phase 1 clinical trials, could help prevent weight regain post-GLP-1 analogue use by mimicking the incretin hormone to suppress appetite and regulate blood sugar, thus aiding in the management of obesity and diabetes
Sex differences may help explain these findings, as certain diabetes-related complications, such as coronary artery disease, tend to be more prevalent in men, whereas conditions like retinopathy are more commonly observed in women. Reference: Hathaway JT, et al