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However, some gout patients with elevated 24-hour urine uric acid, as described in Japanese cohorts, have renal uric overload due to intestinal ABCG2 dysfunction without uric acid overproduction ( Figure 1 - 5 )

Roehrborn, C

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The trials results support the development of Sanionas Tesomet, a formulation comprising tesofensine, which is currently in Phase 2 for rare eating disorders