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These techniques generate objective, repeatable data and enable sensitive detection of micro-leaks that conventional dye ingress or microbial challenge tests may fail to identify

J Physiol Pharmacol 53:3950 Laneuville O, Breuer DK, Dewitt DL, Hla T, Funk CD, Smith WL (1994) Differential inhibition of human prostaglandin endoperoxidase H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs