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For instance, in June 2024, Boehringer Ingelheim and Zealand Pharma reported notable efficacy of survodutide, their dual agonist targeting GLP-1 and glucagon receptors, in reducing liver fibrosis among patients with metabolic dysfunction-associated steatohepatitis (MASH)
While current evidence does not establish a direct causal relationship between tirzepatide and gastrointestinal bleeding, tirzepatide's known gastrointestinal effectsincluding nausea, diarrhea, vomiting, and constipationmay indirectly contribute to conditions that cause rectal bleeding
