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A cardiac magnetic resonance substudy of the SUMMIT trial showed that tirzepatide treatment led to a placebo-corrected reduction of left ventricular mass by 11 g ([95% CI 419 g]

Until then, the notification said GLP-1 RAs should only be prescribed for their licensed indication, and clinicians should avoid initiating people with T2DM on GLP-1 RAs for the duration of the national shortage