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A subset of patients (about 15 to 20%) discontinue due to side effects, mostly mood changes, paresthesia, or insomnia

Reprogramming the lipid metabolism of dendritic cells in tumor immunomodulation and immunotherapy

The treatment involves injecting a solution of glutathione, a powerful antioxidant, into the bloodstream

Moreover, UV radiation can activate the proopiomelanocortin (POMC) gene and thereby enhance the production of alpha-melanocyte stimulating hormone (-MSH) and adrenocorticotropic hormone (ACTH) which can lead to increased PKA and melanogenesis (Im et al., 2002)

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