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Precautions Prior to taking vitamin B12, tell the physician that you have: A cold or an allergy that affects your nasal cavity and the signs you develop A kidney disease A liver disease Any kind of infection An iron deficiency A folic acid deficiency An allergy to vitamin B12 or cobalt A lebers disease as cyanocobalamin can trigger optical nerve damage and blindness A pregnancy, a plan to get pregnant or a breastfeeding baby.