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Skin that is chronically dehydrated is less pliable and more prone to damage when stretched

In support, of this hypothesis, one study of women with lipedema and obesity noted a mismatch in the number of lymphatic vessels and the increased numbers of blood vessels in affected tissue (60)

This is crucial for maintaining normal cellular glucose metabolism and preventing the occurrence of related metabolic diseases

Even though the data is extensive it is not enough to explain any relationship between these molecules and the independent MetS factors, or any mechanism by which these molecules could be involved in the pathophysiology