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Thus, NO ultimately acts as an antioxidant by shunting superoxide to peroxynitrite to nitrate

J.LuitseM

The reduction of the NADP pool suggests that the electron influx into the NADP pool by metabolism more than compensates for the electron efflux to the antioxidant systems, and that glutathione reductase activity, catalysing the reduction of glutathione from NADPH, is limiting under the specific conditions of reoxygenation after hypoxia