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It can also restrict a persons activity and mobility, which in turn can exacerbate problems that tend to diminish health and quality of life in older adults problems such as social isolation, depression, and muscle loss, known as sarcopenia

Participants received either 12mg or 36mg of orforglipron, or 7mg or 14mg of oral semaglutide, over the course of a year

Diets high in added sugars can blunt GLP-1 release over time, disrupting gut hormone signaling and contributing to blood sugar spikes that overwhelm the bodys natural appetite regulation