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The fear that this might be permanent

Muscle is metabolically active tissue, meaning it burns calories at rest

doi: 10.1080/21641846.2019.1653471 33 GandaseguiIMLakaLAGargiuloPAGomez-EstebanJCSanchezJVL

More serious but rare adverse events include pancreatitis (0.2% incidence), gallbladder disease requiring surgical intervention, and medullary thyroid carcinoma risk in genetically predisposed individuals (contraindicated in patients with personal or family history of MTC or MEN2 syndrome)