Sahin E, Colla S, Liesa M, Moslehi J, Mller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, Shukla SA, Jaskelioff M, Martin ES, Heffernan TP, DePinho RA (2011) Telomere dysfunction induces metabolic and mitochondrial compromise
Other interesting contributors are the complement proteins C1q and CR3 (Veerhuis et al., 2011) which are highly produced in the microglia as crucial factors in synapse pruning and are highly present in CSF of AD patients with emerging evidence about their role in A pathogenesis (Fatoba et al., 2021)
Growth hormone is a potent driver of lipolysis (fat breakdown) and supports muscle protein synthesis, satellite cell activation, and lean mass maintenance (11)
DHT (dihydrotestosterone) is the primary culprit in androgenetic alopecia