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Research Considerations Across the preclinical literature, BPC-157 is consistently described as well tolerated with no established lethal dose in animal toxicology, and injection-site reactions among the few commonly noted effects

Gomes MB, Negrato CA (2014) Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases

Zhang et al., 2018), mutations in -Syn proteins undergo misfolding in transcription-translation to produce toxicity, and defective mitophagy further exacerbates neurotoxicity, leading to neuronal loss or damage (Wang et al., 2018)

Collagen and fibroblast activity: In animal studies, BPC-157 has been associated with altered fibroblast activity and collagen deposition patterns