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This idea that we have a time window within which to work, potentially up to three hours, is exciting and may be clinically important, McGavern said

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Radiotherapy resistance in advanced PCa arises from multifactorial mechanisms, including enhanced DNA repair, cancer stem cell (CSC) persistence, immunosuppressive TME, and metabolic reprogramming [72,73]

They found that a moderate Vit C concentration of 100 M prevented cell damage induced by H 2 O 2 , increasing viability, reducing apoptosis, and attenuating intracellular ROS levels, but a higher concentration of Vit C had no effects